Table 2.
Prevalence of back pain symptoms at visit 2 as a function of incident vertebral fracture between baseline and visit 2.
| No incident VF | Incident radiographic only VF | Incident radiographic plus clinical VF | ||||||
|---|---|---|---|---|---|---|---|---|
| % | PR (95%CI) |
% | Age, race, clinic- adjusted PR (95%CI) |
MV-adjusted PR* (95%CI) |
% | Age, race, clinic-adjusted PR (95%CI) |
MV-adjusted PR* (95%CI) |
|
| All participants (n=4,393)† | ||||||||
| Any back pain | 59.4 | 1.0 (ref) | 70.4 | 1.2 (1.1–1.3) | 1.2 (1.1–1.3) | 92.9 | 1.6 (1.4–1.8) | 1.6 (1.4–1.9) |
| Severe back pain | 3.9 | 1.0 (ref) | 8.3 | 2.1 (1.3–3.6) | 1.9 (1.1–3.3) | 17.9 | 4.5 (2.0–10.1) | 3.4 (1.2–9.8) |
| Bother by back pain most or all the time | 12.8 | 1.0 (ref) | 21.9 | 1.7 (1.3–2.3) | 1.7 (1.3–2.2) | 50.0 | 3.9 (2.7–5.7) | 4.0 (2.5–6.4) |
| Limited usual activities due to back pain | 17.6 | 1.0 (ref) | 34.3 | 1.9 (1.6–2.4) | 1.9 (1.5–2.4) | 64.3 | 3.7 (2.8–4.8) | 3.5 (2.2–5.5) |
| Participants with no baseline back pain (n=1,453)† | ||||||||
| Any back pain | 30.1 | 1.0 (ref) | 43.9 | 1.4 (1.0–2.0) | 1.5 (1.1–2.0) | 90.9 | NC‡ | NC‡ |
| Severe back pain | 1.6 | 1.0 (ref) | 4.6 | NC** | NC** | 27.3 | NC‡ | NC‡ |
| Bother by back pain most or all the time | 2.8 | 1.0 (ref) | 4.6 | 1.7 (0.5–5.4) | 1.9 (0.6–6.0) | 63.6 | NC‡ | NC‡ |
| Limited usual activities due to back pain | 4.9 | 1.0 (ref) | 13.6 | 2.8 (1.5–5.4) | 2.7 (1.4–5.2) | 72.7 | NC‡ | NC‡ |
| Participants with baseline back pain (n=2,940)† | ||||||||
| Any back pain | 73.7 | 1.0 (ref) | 87.4 | 1.2 (1.1–1.3) | 1.2 (1.1–1.3) | 94.1 | NC‡ | NC‡ |
| Severe back pain | 5.0 | 1.0 (ref) | 10.7 | 2.0 (1.1–3.7) | 1.6 (0.8–3.0) | 11.8 | NC‡ | NC‡ |
| Bother by back pain most or all the time | 17.7 | 1.0 (ref) | 33.0 | 1.8 (1.4–2.4) | 1.7 (1.3–2.3) | 41.2 | NC‡ | NC‡ |
| Limited usual activities due to back pain | 23.8 | 1.0 (ref) | 47.6 | 2.0 (1.4–2.4) | 1.8 (1.3–2.4) | 58.8 | NC‡ | NC‡ |
VF = vertebral fracture; PR = prevalence ratio; CI = confidence intervals; MV = multivariable; NC = not calculable.
Multivariable models adjusted for baseline age, race, clinic site, IADL impairment, lumbar spine BMD, prevalent radiographic VF, history of any fall in the year before baseline, baseline status for corresponding back pain symptom category, and visit 2 analgesic use.
Among all 4,393 participants, 4,196 had no incident VF, 169 had an incident radiographic only VF, and 28 had an incident radiographic plus clinical VF. Among the 2,940 participants with baseline back pain, 2,820 had no incident VF, 103 had an incident radiographic only VF, and 17 had an incident radiographic plus clinical VF. Among the 1,453 participants without baseline back pain, 1,376 had no incident VF, 66 had an incident radiographic only VF, and 11 had an incident radiographic plus clinical VF.
Results not modeled because the number of incident radiographic plus clinical VF was too small in this subgroup to provide stable estimates of risk of this back pain outcome.