Table 3.
MIC and MBC values of essential oils or their components tested in vitro against food borne pathogens in several recent studies
| EO | MIC (w/v) | MBC (w/v) | Microbial strains tested | References |
|---|---|---|---|---|
| Rosmarinus officinalis | 4.4 mg/mL | 4.4 mg/mL | Escherichia coli | Mathlouthi et al. (2015) |
| 8.8 mg/mL | NA | Salmonella Indiana | ||
| 8.8 mg/mL | NA | Listeria innocua | ||
| NA | NA | Staphylococcus aureus | ||
| NA | NA | Bacillus subtilis | ||
| 10.0 mg/mL | 10.0 mg/mL | Clostridium perfringens | Radaelli et al. (2016) | |
| 25 mg/mL | 50 mg/mL | Salmonella Typhimurium ATCC 1408 | Miladi et al. (2016) | |
| 25 mg/mL | 50 mg/mL | Salmonella Typhimurium LT2 DT104 | ||
| 12.5 mg/mL | 25 mg/mL | Salmonella spp. (S1: 6554)a | ||
| 12.5 mg/mL | 25 mg/mL | Salmonella spp. (S2: 6877)a | ||
| 12.5 mg/mL | 50 mg/mL | Salmonella spp. (S3: 6907)a | ||
| 25 mg/mL | 50 mg/mL | Salmonella spp. (S4: 7215)a | ||
| 25 mg/mL | 50 mg/mL | Salmonella spp. (S5: 7466)a | ||
| 12.5 mg/mL | 25 mg/mL | Salmonella spp. (S6: 7643)a | ||
| 12.5 mg/mL | 50 mg/mL | Salmonella spp. (S7: 7945)a | ||
| 12.5 mg/mL | 25 mg/mL | Salmonella spp. (S8: 9487)a | ||
| 12.5 mg/mL | 25 mg/mL | Salmonella spp. (S9: 9340)a | ||
| 12.5 mg/mL | 25 mg/mL | Salmonella spp. (S10: 9681)a | ||
| 12.5 mg/mL | 25 mg/mL | Salmonella spp. (S11: 9812)a | ||
| 25 mg/mL | 50 mg/mL | Salmonella spp. (S12: 9983)a | ||
| Origanum sp. | 0.9 mg/mL | 1.12 mg/mL | Escherichia coli | Mathlouthi et al. (2015) |
| 0.9 mg/mL | 1.12 mg/mL | Salmonella Indiana | ||
| 0.9 mg/mL | 1.12 mg/mL | Listeria innocua | ||
| 0.9 mg/mL | 1.12 mg/mL | Staphylococcus aureus | ||
| 2.25 mg/mL | 2.25 mg/mL | Bacillus subtilis | ||
| Origanum majorana | 5.0 mg/mL | 5.0 mg/mL | Clostridium perfringens | Radaelli et al. (2016) |
| Origanum vulgare ecotype F | 50 μg/mL | 50 μg/mL | Bacillus cereus ATCC 11778 | De Martino et al. (2009) |
| 50 μg/mL | 50 μg/mL | Bacillus subtilis ATCC 6633 | ||
| 50 μg/mL | 50 μg/mL | Staphylococcus aureus ATCC 2592 | ||
| 50 μg/mL | 100 μg/mL | Streptococcus faecalis ATTC 29212 | ||
| 50 μg/mL | 100 μg/mL | Escherichia coliATCC 25922 | ||
| 100 μg/mL | 100 μg/mL | Proteus mirabilis ATCC 25933 | ||
| 100 μg/mL | > 100 μg/mL | Proteus vulgaris ATCC 13315 | ||
| > 100 μg/mL | > 100 μg/mL | Pseudomonas aeruginosa ATCC 27853 | ||
| 100 μg/mL | 100 μg/mL | Salmonella Typhi Ty2 ATCC 19430 | ||
| Origanum vulgare ecotype S | 50 μg/mL | 50 μg/mL | Bacillus cereus ATCC 11778 | |
| 50 μg/mL | 100 μg/mL | Bacillus subtilis ATCC 6633 | ||
| 50 μg/mL | 50 μg/mL | Staphylococcus aureus ATCC 2592 | ||
| 50 μg/mL | 100 μg/mL | Streptococcus faecalis ATTC 29212 | ||
| 100 μg/mL | 100 μg/mL | Escherichia coliATCC 25922 | ||
| 100 μg/mL | 100 μg/mL | Proteus mirabilis ATCC 25933 | ||
| 100 μg/mL | 100 μg/mL | Proteus vulgaris ATCC 13315 | ||
| > 100 μg/mL | > 100 μg/mL | Pseudomonas aeruginosa ATCC 27853 | ||
| 100 μg/mL | 100 μg/mL | Salmonella Typhi Ty2 ATCC 19430 | ||
| Origanum vulgare ecotype SG | 50 μg/mL | 100 μg/mL | Bacillus cereus ATCC 11778 | |
| 50 μg/mL | 100 μg/mL | Bacillus subtilis ATCC 6633 | ||
| 100 μg/mL | 100 μg/mL | Staphylococcus aureus ATCC 2592 | ||
| 100 μg/mL | 100 μg/mL | Streptococcus faecalis ATTC 29212 | ||
| 100 μg/mL | 100 μg/mL | Escherichia coliATCC 25922 | ||
| > 100 μg/mL | > 100 μg/mL | Proteus mirabilis ATCC 25933 | ||
| > 100 μg/mL | > 100 μg/mL | Proteus vulgaris ATCC 13315 | ||
| > 100 μg/mL | > 100 μg/mL | Pseudomonas aeruginosa ATCC 27853 | ||
| > 100 μg/mL | > 100 μg/mL | Salmonella Typhi Ty2 ATCC 19430 | ||
| Origanum compactum | 0.5 μL/mL | 0.5 μL/mL | Listeria monocytogenes NCTC 11994 | Mith et al. (2014) |
| 0.25 μL/mL | 0.25 μL/mL | Listeria monocytogenes S0580 | ||
| Origanum compactum | 0.5 μL/mL | 0.5 μL/mL | Salmonella Typhimurium ATCC 14028 | |
| 0.25 μL/mL | 0.5 μL/mL | Salmonella Typhimurium S0584 | ||
| 0.25 μL/mL | 0.5 μL/mL | Escherichia coli O157:H7 ATCC 35150 | ||
| 0.5 μL/mL | 0.5 μL/mL | Escherichia coli O157:H7 S0575 | ||
| Origanum heracleoticum | 0.25 μL/mL | 0.25 μL/mL | Listeria monocytogenes NCTC 11994 | |
| 0.25 μL/mL | 0.25 μL/mL | Listeria monocytogenes S0580 | ||
| 0.125 μL/mL | 0.125 μL/mL | Salmonella Typhimurium ATCC 14028 | ||
| 0.25 μL/mL | 0.25 μL/mL | Salmonella Typhimurium S0584 | ||
| 0.25 μL/mL | 0.25 μL/mL | Escherichia coli O157:H7 ATCC 35150 | ||
| 0.25 μL/mL | 0.25 μL/mL | Escherichia coli O157:H7 S0575 | ||
|
Mentha×piperita
Ocimum basilicum Pimpinella anisum |
10.0 mg/mL | 10.0 mg/mL | Clostridium perfringens | Radaelli et al. (2016) |
| 5.0 mg/mL | 5.0 mg/mL | |||
| 10.0 mg/mL | 20.0 mg/mL | |||
| Thymus vulgaris | 1.25 mg/mL | 1.25 mg/mL | ||
| 1.56 mg/mL | 3.12 mg/mL | Salmonella Typhimurium ATCC 1408 | Miladi et al. (2016) | |
| 1.56 mg/mL | 1.56 mg/mL | Salmonella Typhimurium LT2 DT104 | ||
| S. strains isolated from food | ||||
| 1.56 mg/mL | 3.12 mg/mL | Salmonella spp. (S1: 6554) | ||
| 1.56 mg/mL | 1.56 mg/mL | Salmonella spp. (S2: 6877) | ||
| 1.56 mg/mL | 1.56 mg/mL | Salmonella spp. (S3: 6907) | ||
| 1.56 mg/mL | 3.12 mg/mL | Salmonella spp. (S4: 7215) | ||
| 1.56 mg/mL | 1.56 mg/mL | Salmonella spp. (S5: 7466) | ||
| 1.56 mg/mL | 1.56 mg/mL | Salmonella spp. (S6: 7643) | ||
| 0.78 mg/mL | 1.56 mg/mL | Salmonella spp. (S7: 7945) | ||
| 1.56 mg/mL | 1.56 mg/mL | Salmonella spp. (S8: 9487) | ||
| 0.78 mg/mL | 1.56 mg/mL | Salmonella spp. (S9: 9340) | ||
| 1.56 mg/mL | 1.56 mg/mL | Salmonella spp. (S10: 9681) | ||
| 0.39 mg/mL | 0.39 mg/mL | Salmonella spp. (S11: 9812) | ||
| 1.56 mg/mL | 1.56 mg/mL | Salmonella spp. (S12: 9983) | ||
| Thymus vulgaris thymoliferum | 0.5 μL/mL | 0.5 μL/mL | Listeria monocytogenes NCTC 11994 | Mith et al. (2014) |
| 0.25 μL/mL | 0.25 μL/mL | Listeria monocytogenes S0580 | ||
| 0.25 μL/mL | 0.5 μL/mL | Salmonella Typhimurium ATCC 14028 | ||
| 0.25 μL/mL | 0.5 μL/mL | Salmonella Typhimurium S0584 | ||
| 0.25 μL/mL | 0.25 μL/mL | Escherichia coli O157:H7 ATCC 35150 | ||
| 0.25 μL/mL | 0.5 μL/mL | Escherichia coli O157:H7 S0575 | ||
| Thymus capitatus | 0.5 μL/mL | 0.5 μL/mL | Listeria monocytogenes NCTC 11994 | |
| 0.5 μL/mL | 1 μL/mL | Listeria monocytogenes S0580 | ||
| 1 μL/mL | 1 μL/mL | Salmonella Typhimurium ATCC 14028 | ||
| 0.5 μL/mL | 1.5 μL/mL | Salmonella Typhimurium S0584 | ||
| 0.5 μL/mL | 1 μL/mL | Escherichia coli O157:H7 ATCC 35150 | ||
| 0.25 μL/mL | 0.25 μL/mL | Escherichia coli O157:H7 S0575 | ||
| Thymus daenensis | 4.0 mg/mL | 4.0 mg/mL | Escherichia coli | Moghimi et al. (2016) |
| Satureja montana | 0.78 mg/mL | 0.78 mg/mL | Salmonella typhimurium ATCC 1408 | Miladi et al. (2016) |
| 0.78 mg/mL | 0.78 mg/mL | Salmonella typhimurium LT2 DT104 | ||
| 0.39 mg/mL | 0.39 mg/mL | Salmonella spp. (S1: 6554)a | ||
| 0.39 mg/mL | 0.39 mg/mL | Salmonella spp. (S2: 6877)a | ||
| 0.39 mg/mL | 0.39 mg/mL | Salmonella spp. (S3: 6907)a | ||
| 0.39 mg/mL | 0.39 mg/mL | Salmonella spp. (S4: 7215)a | ||
| 0.39 mg/mL | 0.39 mg/mL | Salmonella spp. (S5: 7466)a | ||
| 0.39 mg/mL | 0.39 mg/mL | Salmonella spp. (S6: 7643)a | ||
| 0.39 mg/mL | 0.39 mg/mL | Salmonella spp. (S7: 7945)a | ||
| 0.39 mg/mL | 0.78 mg/mL | Salmonella spp. (S8: 9487)a | ||
| 0.39 mg/mL | 0.39 mg/mL | Salmonella spp. (S9: 9340)a | ||
| 0.39 mg/mL | 0.39 mg/mL | Salmonella spp. (S10: 9681)a | ||
| 0.39 mg/mL | 0.39 mg/mL | Salmonella spp. (S11: 9812)a | ||
| 0.39 mg/mL | 0.78 mg/mL | Salmonella spp. (S12: 9983)a | ||
| Cinnamomum cassia | 0.5 μL/mL | 0.5 μL/mL | Listeria monocytogenes NCTC 11994 | Mith et al. (2014) |
| 0.25 μL/mL | 0.25 μL/mL | Listeria monocytogenes S0580 | ||
| 0.25 μL/mL | 1 μL/mL | Salmonella Typhimurium ATCC 14028 | ||
| 0.25 μL/mL | 1 μL/mL | Salmonella Typhimurium S0584 | ||
| 0.5 μL/mL | 1 μL/mL | Escherichia coli O157:H7 ATCC 35150 | ||
| 0.25 μL/mL | 0.25 μL/mL | Escherichia coli O157:H7 S0575 | ||
| Cinnamomum verum | 0.5 μL/mL | 0.5 μL/mL | Listeria monocytogenes NCTC 11994 | Mith et al. (2014) |
| 0.25 μL/mL | 0.5 μL/mL | Listeria monocytogenes S0580c | ||
| 0.5 μL/mL | 0.5 μL/mL | Salmonella Typhimurium ATCC 14028 | ||
| 0.5 μL/mL | 1 μL/mL | Salmonella Typhimurium S0584 | ||
| 0.5 μL/mL | 0.5 μL/mL | Escherichia coli O157:H7 ATCC 35150 | ||
| 0.25 μL/mL | 0.5 μL/mL | Escherichia coli O157:H7 S0575 | ||
| Eugenia caryophyllus | 1 μL/mL | > 1.5 μL/mL | Listeria monocytogenes NCTC 11994 | |
| 1 μL/mL | > 1.5 μL/mL | Listeria monocytogenes S0580 | ||
| 1 μL/mL | 1.5 μL/mL | Salmonella Typhimurium ATCC 14028 | ||
| 1 μL/mL | 1.5 μL/mL | Salmonella Typhimurium S0584 | ||
| 1 μL/mL | 1 μL/mL | Escherichia coli O157:H7 ATCC 35150 | ||
| 1 μL/mL | 1 μL/mL | Escherichia coli O157:H7 S0575 |
NA no antimicrobial activity, MIC minimum inhibitory concentration, MBC minimum bactericide concentration
a Salmonella strains isolated from food