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. 2017 Nov 10;7:259. doi: 10.3389/fonc.2017.00259

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Copyright © 2017 Parra, Pollack, Chinea, Abramowitz, Marples, Munera, Castillo, Kryvenko, Punnen and Stoyanova.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Associations of well-perfused region of interest (ROI_wp) volume and quantitative DCE features with Gleason Score. (A) Associations (Spearman correlation coefficient and p-values) between peripheral zone ROI_wp and GS divided in 3 (left) and 4 (right) groups; (B) association of the six quantitative DCE features, calculated from the signal-vs-time curve S_ROI of pzROI_wp and GS; (C) The same as in (B) but after normalization with the signal-vs-time from the muscle reference; significant correlations are highlighted in red. (D) The same as in (C), but four groups for GS were considered.