Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Nov 10;8:598. doi: 10.3389/fneur.2017.00598

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 Weideman, Barbour, Tapia-Maltos, Tran, Jackson, Kosa, Komori, Wichman, Johnson, Greenwood and Bielekova.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

MS Severity Score (MSSS) and Age Related MS Severity Score (ARMSS) predict development of future disability measured with CombiWISE slope, but not Expanded Disability Status Scale (EDSS) slope. (A,B) Cross-sectional MSSS and ARMSS measured at the first clinic visit do not predict future accumulation of disability measured by EDSS regression slopes. (C,D) Cross-sectional MSSS and ARMSS measured at the first clinic visit correlate with longitudinal CombiWISE regression slopes derived from subsequent longitudinal follow-up. MSSS, ARMSS, and CombiWISE values were calculated according to published formulas (3, 5, 10), and subsequent EDSS and CombiWISE regression slopes were derived using least squares fitting (see Materials and Methods). Patients were prospectively followed for an average of 4.49 years. Correlations are shown for the entire cohort (n = 201).