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. 2017 Nov 10;8:598. doi: 10.3389/fneur.2017.00598

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Copyright © 2017 Weideman, Barbour, Tapia-Maltos, Tran, Jackson, Kosa, Komori, Wichman, Johnson, Greenwood and Bielekova.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CombiWISE submenu within the Shiny web application. This submenu allows the user to input values for four scales [Expanded Disability Status Scale (EDSS), SNRS, Timed 25-Foot Walk (T25FW), and 9-Hole Peg Test (9HPT)] to compute CombiWISE (10). The values for EDSS (0, 1–10, incrementing by 0.5 where 0 is no disability and 10 is deceased) and SNRS (0–100, incrementing by 1.0 where 100 is no disability and 0 is deceased) are entered via sliding scales, and the T25FW and 9HPT are entered as free text. The T25FW and 9HPT have maximum time limits of 180 s (3 min) and 300 s (5 min), respectively. If these limits are surpassed, the application will prompt the user to round the value to the testing limit. The application controls for the entry of nonsensical data (e.g., 0 s trial) or non-numeric data (e.g., fifteen rather than 15) as demonstrated in Figure 11.