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. 2017 Nov 14;7:15564. doi: 10.1038/s41598-017-15725-7

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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NTP treatment ameliorates imiquimod-induced psoriasis-like skin inflammation in mice. (a) The experimental scheme for imiquimod-induced psoriasis-like skin inflammation in mice. Imiquimod was applied onto the shaved back skin every day for 5 days. The mice were treated with NTP on days 3 and 4. (b) Psoriasis-like skin inflammation was induced and NTP treatment inhibited the psoriasis-like skin inflammation in mice. (c) H&E staining of the mouse back skin. (d) NTP treatment reduced epidermal thickness. The thickness was measured in several regions of the skin section. The epidermal thickness does not include hair follicles. n = 5. **P < 0.005. Bar = 100 µm.