Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Nov 14;7:15588. doi: 10.1038/s41598-017-15783-x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Virions of the ΔM25 mutant are smaller. Transmission electron microscopy of ultrathin-sections of MEF infected with the ΔM25 mutant (a–f, and h) or WT MCMV (g). Cells infected with the mutant virus (f: overview, N = nucleus, E = extracellular space; (a–e,h): higher magnifications) assemble nuclear capsids (a), primary enveloped capsids (b, arrowheads indicate the outer nuclear membrane), cytosolic capsids in proximity to microtubules (c, arrowheads point at a microtubule), secondary enveloped virus particle (d, arrowheads indicate the vesicle membrane) and extracellular virions (e). Diameters (i) and the sectioned tegumented area (j) of cytoplasmic virions were measured for 10 virions each (g, WT MCMV; h, ΔM25 mutant; arrowheads indicate the viral membrane). Means ± SD are depicted and statistical analysis was done using the paired t-test. ***P < 0.001. Scale bars, 200 nm.