Table 2.

Expression of genes grouped in various categories in eAT, mAT and sAT biopsies.

	eAT	mAT	sAT
Thermogenesis	−1.10 ± 0.10a	−1.08 ± 0.10a	−2.07 ± 0.10b***
Beige	−0.57 ± 0.16a	−1.11 ± 0.16b*	−2.22 ± 0.16c***
White	−1.15 ± 0.09c***	0.11 ± 0.09b	0.51 ± 0.09a
Immune	−1.68 ± 0.12a	−1.82 ± 0.12a	−2.59 ± 0.12b***
Extracellular matrix	−1.00 ± 0.08	−1.06 ± 0.08	−1.12 ± 0.08
Oxidative stress	−1.15 ± 0.12a	−1.07 ± 0.12a	−2.03 ± 0.12b***
AT growth & function	1.08 ± 0.11a**	0.88 ± 0.11a*	0.52 ± 0.11b

Data are expressed as log of least square means ± SE, n = 53. Genes were grouped in various categories as the following: Ucp1, Ppargc1a, Prdm16, Cpt1b, Cox4i1 as ‘thermogenesis’-related genes; Tbx1, Tmem26, Tnfrsf9, P2rx5, Slc36a2 as ‘beige’-related genes’; Shox2, Hoxc9, Slc7a10, Lep as ‘white’-related genes; Il6, Ccl2, Tnf, Ccl18, Mrc1, Cd68 as ‘immune’-related genes; Col6a3, Col3a1, Mmp9, Timp1 as ‘extracellular matrix’-related genes; Hif1a, Ncf1, Cyba, Tgfb1 as ‘oxidative stress’-related genes; Slc2a4, Adipoq, Pparg, Fabp4, Cebpa as the ‘AT growth and function’-related genes. Groups were compared using a multivariate randomized block ANOVA model. Superscripts represent significance of P ≤ 0.05. *Represents P ≤ 0.05, **represents P ≤ 0.01, ***represents P ≤ 0.001. AT: Adipose tissue.