Table 1.

Summary of previous studies of food anticipatory activity in Period mutant mice.

Genotype	Genetic background	Age (weeks)	Length of food availability	RF phase	Results	Reference
Per1 −/−	C57BL/6 × 129SvEvBrd	12 to 28	8 h	ZT4–12	FAA present	10
	C57BL/6 × 129SvEvBrd	Not reported	6 h	ZT6–12	FAA present	11
	C57BL/6 J (>N12)	8	4 h	ZT4–8	FAA present	12
mPer2 Brdm1−/−	C57BL/6 × 129SvEvBrd	12 to 28	8 h	ZT4–12	FAA absent	10
	C57BL/6 × 129SvEvBrd	Not reported	6 h	ZT6–12	FAA absent	11
	C57BL/6 J (>N12)	8	4 h	ZT4–8	FAA very weak or absent	12
mPer2 ldc−/−	129/C57BL/6	7 to 9	3 h	ZT6–9	FAA present	8
mPer1 ldc−/− / mPer2 ldc−/−	129	7 to 9	3 h	ZT6–9	FAA present	8
mPer1 ldc−/− / mPer2 ldc−/− / mPer3 −/−	C57BL/6 J	9 to 20	6 h	ZT8–14	FAA present	9

^*All studies were performed in 12 L:12D, except the triple Per1/2/3 mutant mice study that was performed in 18L:6D. Wheel-running food anticipatory activity (FAA) was measured during restricted feeding (RF) in mice with intact (not lesioned) SCN. Results from studies where caloric restriction was combined with restricted feeding are not reported.