Table 6.
Integrated MSNA responses to the FRC-RBRalt protocol
| Baseline | FRC1 | RBR1 | FRC2 | RBR2 | FRC3 | RBR3 | |
|---|---|---|---|---|---|---|---|
| Burst frequency, bursts/min | 18 ± 7 | 40 ± 7*† | 14 ± 7 | 41 ± 6*† | 20 ± 7 | 53 ± 8*† | 19 ± 8 |
| Burst incidence, bursts/100 hb | 29 ± 10 | 69 ± 9*† | 22 ± 12 | 69 ± 13*† | 30 ± 10 | 91 ± 8*† | 27 ± 9 |
| Burst amplitude, AU | 54 ± 12 | 75 ± 18* | 54 ± 7 | 92 ± 13*† | 62 ± 9 | 135 ± 28*† | 80 ± 18* |
| Total MSNA, AU/min | 931 ± 327 | 2,997 ± 969*† | 726 ± 339 | 3,760 ± 827*† | 1,262 ± 515 | 7,076 ± 1,498*† | 1,427 ± 540 |
Values are means ± SD. MSNA, muscle sympathetic nerve activity; FRC, functional residual capacity apnea; RBR, rebreathe; hb, heart beats; AU, arbitrary units.
*
P < 0.001, significantly different from baseline.
†
P < 0.001, significantly different from corresponding RBR period.