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. 2017 Nov 7;124(12):1529–1537. doi: 10.1007/s00702-017-1799-3

Table 3.

Enablers and factors that may suggest the term complex phase PD is a better term to use to denote advanced Parkinson’s disease (PD)

Patient preference
Complexity of mechanisms that lead to the clinical expression of motor and nonmotor subtypes of PD
The need for multimodal and not single biomarkers
The need to take into account various strands of personalised medicine
The fact that advanced PD implies duration of disease while complex refers to the conditional stage and incorporates the concept that early PD can also be complex