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Restoration of TSC1 expression reverses miR-130a driven ovarian cancer cell proliferation and invasion. (a, b) Western blot showed the activation of the mTOR pathway can be rescued by TSC1 overexpression in A2780 and SKOV3 cell lines. (c,d) The colony formation assay and Transwell assay revealed that the promotion effect of proliferation and migration caused by miR-130a could be suppress by introduction of TSC1. *P<0.05; **P<0.01; ***P<0.001
