Figure 7.

miR-130a overexpression promotes tumor growth and metastasis in xenograft. (a, b) Photographs illustrated tumors in xenografts of A2780 and SKOV3 cell lines with or without miR-130a overexpression (n=5). (c,d) The representative images of hematoxylin and eosin (HE)-staining and immunohistochemical staining of TSC1 in lungs isolated from mice that received tail vein injection of SKOV3 and HEY cell lines with and without miR-130a overexpression (n=5). Plot graph illustrates the total numbers of pulmonary metastatic nodules under microscope. *P<0.05; **P<0.01