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. 2017 Sep 1;24(12):2150–2160. doi: 10.1038/cdd.2017.137

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Copyright © 2017 The Author(s)

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Nedd4-2^Ksp1.3 mice have increased BP. (a) SBP and DBP of 6-month-old control and Nedd4-2^Ksp1.3 mice. (b and c) Blood serum aldosterone levels were significantly reduced in the Nedd4-2^Ksp1.3 mice as compared with the control mice at the age of P40 (b) and 6 months (c). All mice were fed a standard laboratory diet. BP was recorded from six to seven mice per genotype (control and Nedd4-2^Ksp1.3) and gender. ****P<0.001