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. 2017 Nov 18;10(11):1640–1646. doi: 10.18240/ijo.2017.11.02

Table 3. Comparison of the histopathologic findings of the keratoconus corneas according to the topographic and pachymetric measurements.

Findings Mean K (D)
CCT (µm)
Yes No P1 Yes No P1
Epithelial thinning 53.8±3.0 47.5±0.7 0.003 320±22 389±40 0.013
Breaks in the Bowman's layer 54.0±3.3 50.8±2.3 0.031 319±25 348±28 0.016
Folds in Descemet's membrane 55.3±2.4 52.1±3.3 0.003 311±16 334±31 0.021
Stromal fiber compaction 55.2±2.5 52.2±3.3 0.010 316±26 329±32 0.325
Superficial iron deposition 54.1±2.6 53.1±3.6 0.420 313±21 330±29 0.068
Collagen filling in Bowman's layer 55.0±3.2 52.7±3.2 0.074 310±22 331±30 0.075
Epithelial scars 55.7±2.8 52.6±3.1 0.012 305±18 331±29 0.001
Breaks in Descemet's membrane 56.0±2.6 52.6±3.1 0.010 308±13 330±29 0.046
Stromal scars 57.2±1.8 52.3±2.8 <0.001 303±11 330±28 0.003
Endothelial cell loss 53.8±3.5 52.0±2.0 0.158 313±32 327±26 0.079

1Mann-Whitney U test. CCT: Central corneal thickness, D: Diopter, K: Keratometry.