Table 2.
Male Rats | |||||||
---|---|---|---|---|---|---|---|
Group | Dose mg/kg bw/day | Total distance travelled (m) | Average speed (m/s) | Absolute turn angle (°) | Rotations of the animal's body | Absolute head turn angle (°) | |
Vehicle Control − (0.5% (w/v) Carboxymethyl Cellulose, aqueous) | |||||||
G1 & G1 (R) | 0 | Mean | 8.784 | 0.015 | 6930 | 6.8 | 10040 |
± S. D. | 5.201 | 0.009 | 4409 | 4.9 | 4882 | ||
n | 15 | 15 | 15 | 15 | 15 | ||
Test Item: Citrus aurantium Extract 50% p-Synephrine | |||||||
G2 | 100 | Mean | 11.355 | 0.019 | 8332 | 8.0 | 10306 |
± S. D. | 4.820 | 0.008 | 2528 | 4.2 | 4294 | ||
n | 10 | 10 | 10 | 10 | 10 | ||
G3 | 300 | Mean | 11.224 | 0.019 | 11111 | 9.4 | 15295S+ |
± S. D. | 2.782 | 0.005 | 4160 | 3.3 | 6098 | ||
n | 10 | 10 | 10 | 10 | 10 | ||
G4 & G4 (R) | 1000 | Mean | 8.925 | 0.015 | 8640 | 7.5 | 12580 |
± S. D. | 6.591 | 0.011 | 5030 | 5.8 | 5489 | ||
n | 15 | 15 | 15 | 15 | 15 | ||
S+/S-: Group mean value is significantly (P < 0.05) higher/lower than the respective value of the vehicle control group. Animals were assessed on days 87 and 88. The duration of the test was 600 s. |
Female Rats | |||||||
---|---|---|---|---|---|---|---|
Group | Dose mg/kg bw/day | Total distance travelled (m) | Average speed (m/s) | Absolute turn angle (°) | Rotations of the animal's body | Absolute head turn angle (°) | |
Vehicle Control − (0.5% (w/v) Carboxymethyl Cellulose, aqueous) | |||||||
G1 & G1 (R) | 0 | Mean | 17.928 | 0.030 | 16103 | 15.7 | 20126 |
± S. D. | 3.716 | 0.006 | 2638 | 3.8 | 1888 | ||
n | 15 | 15 | 15 | 15 | 15 | ||
Test Item: Citrus aurantium Extract 50% p-Synephrine | |||||||
G2 | 100 | Mean | 18.849 | 0.031 | 15821 | 15.4 | 20266 |
± S. D. | 1.506 | 0.002 | 2345 | 3.0 | 1081 | ||
n | 10 | 10 | 10 | 10 | 10 | ||
G3 | 300 | Mean | 17.441 | 0.029 | 15796 | 12.6 | 19290 |
± S. D. | 2.460 | 0.004 | 5978 | 2.0 | 1401 | ||
n | 10 | 10 | 10 | 10 | 10 | ||
G4 & G4 (R) | 1000 | Mean | 18.891 | 0.032 | 16646 | 16.5 | 21225 |
± S. D. | 5.601 | 0.009 | 3117 | 4.7 | 2612 | ||
n | 15 | 15 | 15 | 15 | 15 | ||
Group mean values of treated groups do not differ significantly (P > 0.05) from those of the respective values of the vehicle control group. Animals were assessed on days 87 and 88. The duration of the test was 600 s. |