Table 4.

Summary of Organ Weights Relative to Total Body Weights (%) at Termination (Day 91).

Male Rats
Group	Dose mg/kg/day		Fasting Body Wt. (g)	Adrenals	Testes	Kidneys	Liver	Brain	Thymus	Heart	Spleen	Epididymides
Vehicle Control − 0.5% (w/v) Carboxymethyl cellulose, aqueous only
G1	0	Mean	456.00	0.012	0.86	0.69	2.89	0.53	0.09	0.36	0.18	0.34
		S. D	46.68	0.002	0.08	0.05	0.18	0.05	0.02	0.02	0.02	0.04
		n	10	10	10	10	10	10	10	10	10	10
Test Item: Citrus aurantium 50% p-synephrine
G2	100	Mean	469.20	0.011	0.84	0.66	2.75	0.51	0.11	0.35	0.18	0.34
		S. D	35.12	0.003	0.06	0.05	0.20	0.03	0.03	0.02	0.02	0.03
		n	10	10	10	10	10	10	9	10	10	10
G3	300	Mean	462.90	0.011	0.80	0.70	2.91	0.51	0.11	0.36	0.19	0.32
		S. D	18.78	0.003	0.08	0.09	0.17	0.02	0.04	0.03	0.02	0.04
		n	10	10	10	10	10	10	10	10	10	10
G4	1000	Mean	433.60	0.013	0.82	0.75	2.96	0.53	0.08	0.41S+	0.24	0.32
		S. D	38.57	0.005	0.15	0.22	0.32	0.03	0.02	0.05	0.11	0.05
		n	10	10	10	10	10	10	10	10	10	10

Female Rats
Group	Dose mg/kg/day		Fasting Body Wt. (g)	Adrenals	Ovaries	Kidneys	Liver	Brain	Thymus	Heart	Spleen	Uterus
Vehicle Control − 0.5% (w/v) Carboxymethyl cellulose, aqueous only
G1	0	Mean	278.60	0.023	0.046	0.67	2.70	0.79	0.14	0.39	0.25	0.28
		S. D	23.30	0.006	0.007	0.05	0.14	0.05	0.03	0.03	0.04	0.14
		n	10	10	10	10	10	10	10	10	10	10
Test Item: Citrus aurantium 50% p-synephrine
G2	100	Mean	289.00	0.026	0.046	0.71	2.69	0.75	0.13	0.39	0.23	0.25
		S. D	24.34	0.009	0.008	0.07	0.15	0.06	0.02	0.03	0.02	0.07
		n	10	10	10	10	10	10	10	10	10	10
G3	300	Mean	273.80	0.028	0.043	0.74	2.76	0.82	0.13	0.42	0.24	0.26
		S. D	23.13	0.006	0.010	0.11	0.29	0.07	0.02	0.03	0.04	0.12
		n	10	10	10	10	10	10	10	10	10	10
G4	1000	Mean	280.30	0.027	0.046	0.73	2.90	0.79	0.14	0.43S+	0.24	0.28
		S. D	26.92	0.006	0.011	0.09	0.16	0.08	0.02	0.02	0.03	0.12
		n	10	10	10	10	10	10	10	10	10	10

S+: Group mean value is significantly (P < 0.05) higher than the respective value of the vehicle control group.