Table 5.
Summary of Absolute Organ Weights (g) at Termination of Recovery Period (Day 119).
| Male Rats | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Group | Dose mg/kg/day | Fasting Body Wt. | Adrenals | Testes | Kidneys | Liver | Brain | Thymus | Heart | Spleen | Epididymides | |
| Vehicle Control (0.5% (w/v) Carboxymethyl Cellulose, aqueous only) | ||||||||||||
| G1 (R) | 0 | Mean | 492.80 | 0.054 | 4.14 | 3.09 | 12.73 | 2.27 | 0.39 | 1.63 | 0.82 | 1.69 |
| S. D | 64.31 | 0.007 | 0.46 | 0.34 | 1.79 | 0.13 | 0.13 | 0.14 | 0.08 | 0.27 | ||
| n | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | ||
| Test Item: Citrus aurantium 50% p-synephrine | ||||||||||||
| G4 (R) | 1000 | Mean | 491.00 | 0.06 | 3.82 | 3.18 | 12.48 | 2.24 | 0.42 | 1.57 | 0.77 | 1.71 |
| S. D | 26.68 | 0.01 | 0.36 | 0.86 | 1.47 | 0.10 | 0.15 | 0.15 | 0.11 | 0.20 | ||
| n | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | ||
| Female Rats | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Group | Dose mg/kg/day | Fasting Body Wt. | Adrenals | Ovaries | Kidneys | Liver | Brain | Thymus | Heart | Spleen | Uterus | |
| Vehicle Control (0.5% (w/v) Carboxymethyl Cellulose, aqueous only) | ||||||||||||
| G1 (R) | 0 | Mean | 294.20 | 0.075 | 0.114 | 1.87 | 7.12 | 2.26 | 0.34 | 1.11 | 0.61 | 0.67 |
| S. D | 15.45 | 0.007 | 0.033 | 0.27 | 0.58 | 0.07 | 0.07 | 0.12 | 0.05 | 0.15 | ||
| n | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | ||
| Test Item: Citrus aurantium 50% p-synephrine | ||||||||||||
| G4 (R) | 1000 | Mean | 330.20 | 0.090 | 0.119 | 1.91 | 8.17 | 2.32 | 0.35 | 1.18 | 0.64 | 0.88 |
| S. D | 35.96 | 0.021 | 0.022 | 0.38 | 1.82 | 0.19 | 0.10 | 0.15 | 0.11 | 0.34 | ||
| n | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | ||
| Organ weights of treated rats do not differ significantly (P > 0.05) from those of the control group. | ||||||||||||