Fig. 3.

Lower half of the asymmetric unit, with 2 Fabs in close contact and related by a local dyad that is oblique to the cell. This contact, centered on the elbows of the 2 heavy chains (H and V), is highlighted by the dyad-related red and cyan residues. The interfaces that form this Fab dimer are listed in Table 2, rows Id=4 and Id=5. This 'dimer of Fabs' also occurs in a few differently-packed crystals of similar Fabs (e.g., 4JLR, 4MAU, 3L7F).