Fig. 4.

Asymmetric unit of 5K8A. The dimer in Fig. 3 (Fabs LH and MV) is redrawn here using all surfaces, keeping the red and cyan residues at the dimer interface. Above that dimer, ribbons are used to show the other two Fabs, AB and EF, using the same colors, with dark colors for all heavy chains. Three magenta patches indicate the 3 interfaces where the upper dimer touches the lower (corresponding to rows with Id=6 and 12 in Table 2). The gray cylinder indicates the pseudodyad that runs diagonally thru the center of the asymmetric unit. This pseudodyad corresponds to the twin operator K,H,-L. The upper and lower dimers superimpose with root-mean-square deviation (C-alpha atoms) of 0.0977 nm. The blue cylinders show crystallographic dyads where the F and H chains form key interfaces that are shown in Fig. 5.