Table 2. Comparisons of MRI, TCD, and TPI Measures Among the Three Groups.
| Depressed patients (n=25) | Remitted patients (n=24) | Controls (n=25) | p-value | |
|---|---|---|---|---|
| MRI | ||||
| Total WMH (cm3) | 0.82 (0.83) | 0.63 (0.67) | 0.70 (0.98) | 0.167 |
| Right hemisphere WMH (cm3) | 0.41 (0.44) | 0.32 (0.31) | 0.31 (0.36) | 0.480 |
| Right MCA ASL (arbitrary unit) | 105 (53) | 106 (41.5) | 110.5 (27.25) | 0.450 |
| TCD | ||||
| MCA max velocity (m/s) | 80.9 (39.7) | 100.4 (21.7) | 93.7 (34.9) | 0.100 |
| MCA mean velocity (m/s) | 49.9 (25.5) | 65.1 (20.5) | 56.1 (26.1) | 0.131 |
| MCA PI | 0.88 (0.31) | 0.88 (0.27) | 0.90 (0.24) | 0.956 |
| TPI | ||||
| MaxBTP PtoP (μm) | 115.8 (53.7) | 97.5 (35.1) | 106.4 (50.1) | 0.439 |
| MaxBTP RMS (μm) | 36.1 (17.9) | 31.2 (12.1) | 34.1 (17.5) | 0.484 |
| MeanBTP PtoP (μm) | 24.6 (10) | 20.1 (9.3) | 20.0 (8.7) | 0.046 |
| MeanBTP RMS (μm) | 8.6 (5.3) | 6.7 (3.7) | 7.0 (3.4) | 0.031 |
Abbreviations: ASL, arterial spin labeling; BTP, brain tissue pulsatility; MCA, middle cerebral artery; MRI, magnetic resonance imaging; PI, pulsatility index; PtoP, peak-to-peak; RMS, root mean square; TCD, transcranial Doppler; TPI, tissue pulsatility imaging; WMH, white matter hyperintensities.
Values are expressed as the median (interquartile range). Comparisons were performed with Kruskal–Wallis tests.