Skip to main content
. 2017 Jul 5;42(13):2602–2611. doi: 10.1038/npp.2017.115

Table 3. DAVID 6.7 Analysis.

Gene list input Gene counts Percent of input list Fold enrichments over background Bonferroni corrected p-values
(A) Novel L1s—with overlapping genes Schizophrenia (Normal)
 GO_cellular compartment_FAT        
  GO:0042995~cell projection 18 (NA) 11.76 (NA) 3.03 (NA) 0.0151 (NA)
         
(B) Novel L1s—no overlapping genes        
 GO_cellular compartment_FAT        
  GO:0042995~cell projection 13 (NA) 15.12 (NA) 3.91 (NA) 0.0133 (NA)
         
(C) KNR L1s—with overlapping genes        
 GO_cellular compartment_FAT        
  GO:0044459~plasma membrane part 42 (NA) 21.88 (NA) 1.81 (NA) 0.0242 (NA)
  GO:0005886~plasma membrane 61 (NA) 31.77 (NA) 1.53 (NA) 0.0314 (NA)
  GO:0043005~neuron projection 17 (18) 8.85 (8.53) 4.71 (4.43) 1.43E−04 (1.53E−04)
  GO:0045202~synapse 16 (16) 8.33 (7.58) 4.27 (3.79) 1.16E−03 (5.17E−03)
  GO:0030054~cell junction 18 (19) 9.38 (9.00) 3.29 (3.08) 7.28E−03 (0.0103)
  GO:0042995~cell projection 21 (22) 10.94 (10.43) 2.85 (2.65) 9.43E−03 (0.0182)
         
(D) KNR L1s—no overlapping genes        
 No significant GO terms identified NA (NA) NA (NA) NA (NA) NA (NA)
         
(E) Novel+KNR L1s—no overlapping genes        
 GO_biological process_FAT        
  GO:0042981~regulation of apoptosis NA (15) NA (16.30) NA (3.55) NA (0.0470)
 GO_cellular compartment_FAT        
  GO:0045202~synapse 11 (NA) 9.57 (NA) 4.95 (NA) 0.0120 (NA)

Abbreviations: FAT, filtered annotated terms; GO, Gene Ontology; KNR, known non-reference; NA, not applicable.

‘Overlapping genes’ refers to genes harboring L1s found in both the normal and schizophrenia populations.