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. 2017 Nov 14;2(6):e00046-17. doi: 10.1128/mSystems.00046-17

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Copyright © 2017 d’Hennezel et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 2 — Bacteroidetes bacteria are the main contributors to LPS biosynthesis in the human gut microbiome. (A) Average abundance per sample of genes related to the three main LPS biosynthesis-related functions. (B) Relative contributions of the different phyla to the total LPS-encoding capacity of the gut microbiome determined in both cohorts. The three functions of LPS biosynthesis were pooled. The darker-color set is HMP samples, and the lighter-color set is NVS samples. (C) Contribution of individual species to LPS biosynthesis functions. The average relative abundances of genes related to any of the three LPS-related GO functions are shown for individual species within each phylum. Only species detected in >50% of the donors in each data set are shown. The darker-color set is HMP samples, and the lighter-color set is NVS samples. (D) Correlation of individual-species abundance with stimulation of IL-6 production as determined in panel A. (E) Correlation of individual-species abundance with inhibition of IL-6 production as determined in panel B. Each data point represents one independent experiment. Rs, Spearman rho.