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. 2017 Oct 18;36(22):3309–3324. doi: 10.15252/embj.201796685

Figure EV5. Homology model of the wild‐type SLCO2A1 protein.

Figure EV5

  1. The model was built using I‐TASSER (Iterative Threading ASSEmbly Refinement) server (http://zhanglab.ccmb.med.umich.edu/I-TASSER/). The server selected the crystal structure of the glycerol‐3‐phosphate transporter from Escherichia coli (PDB ID: 1PW4A) as the best template.
  2. A Side view. The dashed line marks the central axis of the molecule. Amino acids for the mutations which are discussed in the text are highlighted and indicated. The transmembrane helixes bearing these amino acids are colored in yellow. Other helixes are shown in green.
  3. Top view.