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. 2017 Sep 28;36(22):3325–3335. doi: 10.15252/embj.201797609

Figure EV4. Depletion of BCAR4 impaired YAP‐dependent tumorigenesis.

Figure EV4

  • A, B
    Ki‐67 (A) and BrdU (B) staining was performed as indicated. Scale bars, 100 μm. The percentages of positive cells are summarized on the right (mean ± s.d., n = 3 biological replicates, Student's t‐test).
  • C
    Tumors excised from nude mice treated with scrambled LNA or BCAR4 LNA (25 mg/kg).
  • D
    Representative immunohistochemical images of LDHA are shown in the xenograft tumors. Scale bar, 200 μm.
  • E
    The relative intensities of LDHA immunohistochemical staining were quantified by Image‐pro plus 6.0 software (Media Cybernetics) (mean ± s.d., n = 3 biological replicates, Student's t‐test, n.s., no significant difference).