-
A–C
Expression of Itgax and Igf1 in PN5 brains of CD11c iDTR mice (n = 6) and WT littermates (n = 3) treated with DTx at days 1 and 3 after birth (A); PN7 brains of CD11c DTA mice (n = 5) and WT littermates (n = 3) (B); PN5 WT brains I.C. injected with saporin toxin conjugated with anti‐CD11c (n = 6) or isotype control antibody (n = 5) (C).
-
D–G
Representative flow cytometry profiles (D) and flow cytometry analysis showing percentage from total microglia (E) and absolute numbers of CD11c+ microglia (F) as well as absolute numbers of total microglia (G) in PN5 WT brains I.C. injected with saporin toxin conjugated with anti‐CD11c (n = 6) or isotype control antibody (n = 5).
Data information: Data are based on at least two experimental repeats. Data are presented as means ± SEM; each
n represents an individual mouse.
P‐values were determined by two‐tailed Mann‐Whitney
U‐test. ns, not significant; *
P <
0.05; **
P <
0.01; ***
P <
0.001.
