Table 3.
Area Under the Curve (AUC) for the ROC Curves
| Test | AUC (±SE) | Best Cutoff (nmol/L) | Sensitivity (%) | Specificity (%) | LR | |
|---|---|---|---|---|---|---|
| + | − | |||||
| Peak salivary cortisol | 0.914 ± 0.026 (0.863–0.965) | 8.6 | 84.7 | 94.6 | 15.819 | 0.161 |
| Peak salivary cortisone | 0.926 ± 0.022 (0.882–0.970) | 33.5 | 84.7 | 88.4 | 7.301 | 0.173 |
| Basal serum cortisol | 0.903 ± 0.024 (0.856–0.951) | 170 | 76.3 | 88.4 | 6.571 | 0.268 |
| Basal salivary cortisol | 0.836 ± 0.036 (0.766–0.906) | 1.7 | 62.7 | 95.5 | 14.047 | 0.390 |
| Basal salivary cortisone | 0.862 ± 0.033 (0.797–0.926) | 12.5 | 72.9 | 88.4 | 6.279 | 0.307 |
Shown are AUCs for the ROC curves of basal serum cortisol, salivary cortisol, and salivary cortisone, as well as post-LDSST peak salivary cortisol and salivary cortisone with the corresponding best cutoff values and their sensitivity, specificity, and likelihood ratios in the patient group (n = 171) when AI (disease) was defined as post-LDSST serum cortisol < 376 nmol/L.
Abbreviation: SE, standard error.