Table 1.
Summary of Current and Historical Surveillance Recommendations and Numbers of Patients Included, in Chronological Order
| Reference | Year | Clinical Review and Biochemical Tests | Total No. of SDHB Patients | No. of SDHB Asymptomatic Carriers | Anatomical Imaging | Functional Imaging |
|---|---|---|---|---|---|---|
| Kirmani and Young | 1993 | Annual | NA; review article | NA | HN CT/MRI every 2 years and TAP MRI every 4 years | 123I-MIBG every 4 years |
| Neumann et al. | 2004 | 53 | 28 | |||
| Benn et al. | 2006 | Annual | 33 | 33 | Neck and TAP CT/MRI every 2 years | Consider 18F-DOPA-PET |
| Srirangalingam et al. | 2008 | Annual | 32 | 11 | Neck and TAP MRI annually | |
| Neumann et al. | 2009 | Annual | NA; review article | NA | Serial MRI of skull base to pelvis (frequency not stated) | Consider 123I-MIBG and 18F-DOPA-PET |
| European Association of Nuclear Medicine guidelines | 2012 | NA; guideline | NA | Choice of nuclear imaging depends on genetic diagnosis and tumor site | ||
| Gimenez-Roqueplo et al. | 2013 | 124 | 85 | First screen with HN MRI + TAP CT (frequency for follow-up surveillance imaging not stated) | First screen with somatostatin receptor scintigraphy | |
| Taieb et al. | 2014 | Annual | NA; review article | NA | HN MRI every 3 years | Consider PET on individual case basis |
| Endocrine Society clinical practice guidelines | 2014 | Annual | NA; guideline | NA | Periodic MRI (frequency not stated) | Reserved for further characterization of detected tumors |
| Jasperson et al. | 2014 | Annual | 33 | 28 | ||
| Favier et al. | 2015 | Annual | NA; review article | NA | Initial HN and TAP CT/MRI and, if negative, 2 to 3 yearly whole-body MRIs | First screen with 111In-pentetreotide scintigraphy or 18F-FDG-PET/CT |
| Tufton et al. | 2016 | Annual | 92 | 65 | Abdomen MRI annually; HN, thorax, and pelvis MRI every 2 years | |
| European Society clinical practice guidelines | 2016 | Annual | NA | NA | TAP MRI every 1 to 2 years for follow-up of resected biochemically silent tumors | |
| Kornaczewski et al. | 2016 | 20 | 14 | Whole-body CT every 5 years | 18F-FDG PET/CT every 5 years | |
| Daniel et al. | 2016 | Annual | 36 | 27 | 2 yearly neck and TAP MRIs | |
| Eijkelenkamp et al. | 2017 | Annual | 93 | 72 | TAP MRI every 2 years; HN MRI every 3 years |
Abbreviations: HN, head and neck; NA, not applicable.