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. 2017 Nov 13;37(23):e00441-17. doi: 10.1128/MCB.00441-17

FIG 4.

FIG 4

Impaired PARK2 mitochondrial translocation in TSC2-deficient cells. (A and B) Representative images of PARK2-HA localization in TSC2+/+ and TSC2−/− MEFs with or without 3 h of CCCP exposure and/or 15 h of Rapa pretreatment. Bars, 20 μm; bars in magnified images, 50 μm. DMSO, dimethyl sulfoxide; DAPI, 4′,6-diamidino-2-phenylindole. (C) Quantification of cells with PARK2-positive mitochondria in CCCP-treated cells from the experiment shown in panel B. The values represent means and SD (n = 3 independent experiments). *, P < 0.05; **, P < 0.01 compared to the indicated control.