TABLE 1.
Competition assays of copper-trafficking mutants
| Relevant genotype of S. Typhimurium straina: |
Mouse strainb | Median CI | No. of mice | P valuec | Fold attenuationd | |
|---|---|---|---|---|---|---|
| A | B | |||||
| ΔcueP | WT | BALB/c | 1.16 | 4 | NS | — |
| ΔcopA ΔgolT | WT | BALB/c | 1.00 | 8 | NS | — |
| ΔcueP ΔcopA ΔgolT | WT | BALB/c | 3.14 | 4 | NS | — |
| ΔcueP ΔcopA ΔgolT | WT | C3H | 2.40 | 6 | NS | — |
| ΔcueP ΔcopA ΔgolT | WT | C57 | 4.30 | 5 | NS | — |
a
The strains used were 14028, JS2089, JS2090, and JS2092.
b
Mouse genetic background: BALB/c, BALB/cAnNHsd; C3H, C3H/HeNHsd; C57, C57BL/6J.
c
By Student's t test comparing CI versus inoculum. NS, not significant.
d
Reciprocal of median CI, if significant. —, CI not significant.