TABLE 2.
Competition assays of ΔsodCI in copper-trafficking mutant backgrounds
| Relevant genotype of S. Typhimurium straina: |
Median CI | No. of mice | P valueb | Fold attenuationc | |
|---|---|---|---|---|---|
| A | B | ||||
| ΔsodCI ΔcueP | ΔcueP | 0.17 | 7 | 0.001 | 6.0 |
| ΔsodCI ΔcopA ΔgolT | ΔcopA ΔgolT | 0.23 | 4 | 0.034 | 4.4 |
| ΔsodCI ΔcopA ΔgolT ΔcueP | ΔcopA ΔgolT ΔcueP | 0.13d | 7 | 0.005 | 7.7 |
| ΔsodCI | WT | 0.15d | 4 | <0.005 | 6.7 |
The strains used were 14028, JS2096, JS192, JS2095, JS2091, JS2097, and JS2092.
By Student's t test comparing CI versus inoculum.
Reciprocal of median CI, if significant.
Not significantly different from one another; P = 0.47.