TABLE 3.
Competition assays addressing the importance of CueP in defense against oxidative stress
| Relevant genotype of S. Typhimurium straina: |
Median CI | No. of mice | P valueb | Fold attenuationc | |
|---|---|---|---|---|---|
| A | B | ||||
| ΔsodCI ΔsodCII | sodCIIres+ ΔsodCI ΔsodCII | 0.21 | 3 | 0.0085 | 4.8 |
| ΔcueP sodCIIres+ | sodCIIres+ | 0.86 | 3 | NS | — |
| ΔcueP ΔsodCI ΔsodCII | ΔsodCI ΔsodCII | 0.64 | 5 | NS | — |
| ΔdsbC ΔdsbG | WT | 1.60 | 5 | NS | — |
| ΔsodCI ΔdsbC ΔdsbG | ΔdsbC ΔdsbG | 0.14 | 5 | <0.0005 | 7.1 |
a
The strains used were 14028, JS2100, JS1176, JS2101, JS2102, JS2098, and JS2099.
b
By Student's t test comparing CI versus inoculum; NS, not significant.
c
Reciprocal of median CI, if significant. —, CI not significant.