Table 1.
Baseline Characteristics (n = 49, Unless Specified Otherwise)
| Variable | Patients |
|---|---|
| Demographic | |
| Age, y | |
| Median | 32.7 |
| IQR | 22.6 to 39.0 |
| Male sex, n (%) | 20 (40.8) |
| Anthropometric | |
| Weight, kg | 71.1 ± 19.6 |
| Height, cm | 151.2 ± 11.0 |
| BMI, kg/m2 | 31.0 ± 7.5 |
| Clinical, n (%) | |
| Spinal level | |
| High | 9 (18.4) |
| Mid | 16 (32.7) |
| Low | 24 (49.0) |
| Nonambulatory | 27 (55.1) |
| Anticonvulsant use | 10 (20.4) |
| Hydrocephalus | 36 (73.5) |
| Fracture | 10 (20.4) |
| Urological intervention | 27 (55.1) |
| Upper tract calculi | 2 (4.1) |
| Renal impairment (eGFR <90 mL/min/1.73 m2; n = 42) | 9 (18.4) |
| Hypogonadism | 5 (10.2) |
| DXA | |
| LTM, kg | 36.9 ± 9.0 |
| FM, kg | 30.4 ± 13.8 |
| Bone mineral content, kg | 2.40 ± 0.51 |
| L1 BMD (n = 32), g/cm2 | 1.04 ± 0.15 |
| L1 Z-score | |
| Median | −1.1 |
| IQR | −1.9 to −0.1 |
| FN BMD (n = 37), g/cm2 | 0.81 ± 0.13 |
| FN Z-score | |
| Median | −1.5 |
| IQR | −2.4 to −0.7 |
| TB BMD (n = 40), g/cm2 | 1.14 ± 0.10 |
| TB Z-score | |
| Median | −0.3 |
| IQR | −1.1 to 0.5 |
| Radius BMD (n = 27), g/cm2 | 0.86 ± 0.11 |
| Radius Z-score | |
| Median | −0.6 |
| IQR | −1.3 to 0.4 |
| Biochemical | |
| Vitamin D (n = 23), nmol/L | 58.0 ± 25.3 |
| Creatinine, mmol/L | |
| Median | 51 |
| IQR | 38 to 84 |
| Bicarbonate, mmol/L | 24.4 ± 3.4 |
| Chloride, mmol/L | 105.5 ± 3.3 |
| ALP (U/L) | |
| Median | 92.5 |
| IQR | 75 to 112.5 |
| GGT (U/L) | |
| Median | 20.5 |
| IQR | 14.5 to 50 |
Abbreviations: ALP, alkaline phosphatase; eGFR, estimated glomerular filtration rate; FN, femoral neck; GGT, γ-glutamyl transpeptidase; TB, total body.