Study ID	Mefloquine participants	Drug comparator(s) (n)	Outcome(s) measured	Results reported
Schlagenhauf 2003	153	Atovaquone‐proguanil (164), doxycycline (153)	POMS¹ Quality of life questionnaire²	POMS: Reports no statistically significant differences between groups. Quality of life questionnaire: Reports no statistically significant differences between groups
van Riemsdijk 2002	58	Atovaquone‐proguanil (61)	POMS¹ NES³	POMS: "Significant deterioration on the domains of depression, anger, fatigue, and vigor. The TMD increased by 7.52 points (95% confidence interval, 3.32 to 11.71 points)" NES: Both groups showed improvement between the first and second measurement. No differences were observed between groups