Figure 2.
The growth charts of the patients carrying heterozygous GHR variants. (a) P1, c.964dupG; (b) P2, c.920_921ins14; (c) P3, c.945+2T>C; and (d) P4, c.899dupC [15]. The time frame of rhIGF-I, rhGH, and rhIGF-I + IGFBP3 treatments are indicated on the growth curves. CDC, Centers for Disease Control and Prevention.