Table 2.

LH, FSH, Estradiol, Testosterone, and Inhibin B Concentrations in Women With Hyperprolactinemia Receiving Vehicle (Saline) and Then Kp-10 Infusion

	Patient 1 (P1)		Patient 2 (P2)		Normal Rangea
	Saline	Kp-10	Saline	Kp-10
LH, IU/L	5.3 ± 2.9 (n = 72)	25.4 ± 10.8b (n = 72)	1.22 ± 0.43 (n = 72)	5.2 ± 2.37b (n = 72)	2.2–8.2
FSH, IU/L	3.6 ± 0.3 (n = 72)	12.1 ± 4.3b (n = 72)	5.5 ± 1.0 (n = 72)	12.2 ± 2.7b (n = 72)	2.4–7.9
Estradiol, pg/mL	18.6 ± 4.5 (n = 12)	47.5 ± 20.9c (n = 12)	16.8 ± 1.9 (n = 12)	24.7 ± 8.6d (n = 12)	18–97
Testosterone, ng/mL	0.78 ± 0.04 (n = 12)	0.92 ± 0.08c (n = 12)	0.62 ± 0.02 (n = 12)	0.69 ± 0.02c (n = 12)	0.3–0.8
Inhibin B, pg/mL	50.5 ± 5.7 (n = 12)	188.0 ± 69.4b (n = 12)	28 ± 2.4 (n = 12)	40.9 ± 6.4c (n = 12)	29–129

Data are presented as mean ± standard deviation. During saline control and Kp-10, 12 measurements of estradiol and inhibin B were performed. To convert estradiol in pg/mL to pmol/L, multiply by 3.671. To convert testosterone values in ng/mL to nmol/L, multiply by 3.467.

^aNormal values were taken from the early follicular phase, days 3 to 6 after onset of menses; data from 51 healthy women [22].

^bP < 0.0001 (Wilcoxon test).

^cP < 0.01 (Wilcoxon test).

^dP < 0.05 (Wilcoxon test).