TABLE 6.
Phyre2 investigator tests
| Gene | Subject | Sample | Isolate | Amino acid position | Amino acid variant (%) | Secondary structure | Structural modifications | ProQ2 quality | Alignment confidence | Residue conservation | Mutational sensitivity |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UL13 | A | 8 | Primary | 190 | A (86), V (14) | α-Helix | No | Medium | Medium | Low | Low |
| UL13 | A | 14 | Recurrent | 229 | D (90), Y (10) | β-Sheet | No | Medium | Good | High | High |
| UL13 | B | 16 | Primary | 288 | R (86), stop (14) | Connector | |||||
| UL13 | B | 19 | Recurrent | 378 | G (86), V (14) | Connector | No | Medium | Good | Low | Low |
| UL21 | B | 16 | Primary | 347 | A (67), T (33) | α-Helix | No | Good | Good | High | High |
| UL30 | B | 16 | Primary | 951 | C (80), Y (20) | β-Sheet | No | Good | Good | Low | Low |
| UL37a | A | 8 | Primary | 493 | P (93) | α-Helix | Yes | Medium | Good | Low | Low |
| UL37a | A | 14 | Recurrent | 493 | H (99) |
a
Represented in Fig. 4.