TABLE 1.
Genetic background of vaccinees and controls and numbers of challenges needed to cause infection with SIVmac251
| Group | Animal ID | MHC class Ia | No. of exposures to infection | Total no. of exposures |
|---|---|---|---|---|
| Controls, vaccine 1 | 2249 | A1*001 | 4 | |
| 2290 | 1 | |||
| 2294 | A1*001 | 1 | ||
| Controls, vaccine 2 | 2302 | 7 | ||
| 2305 | 1 | |||
| 2325 | A1*001, B*017:01 | 1 | 15 | |
| Vaccine 1 | 2317 | 2 | ||
| 2328 | 2 | |||
| 2332 | 2 | |||
| 2337 | 3 | |||
| 13923 | A1*001 | 5 | ||
| 13930 | A1*001 | 2 | 16 | |
| Vaccine 2 | 2275 | 8 | ||
| 2295 | >8b | |||
| 2324 | A1*001, B*017:01 | 6 | ||
| 2338 | A1*001, B*017:01 | 5 | ||
| 13929 | A1*001 | 6 | ||
| 13934 | A1*001 | 2 | >35 |
a
Major histocompatibility complex genotypes associated with slow disease progression.
b
Not infected after 8 exposures.