TABLE 2.
Bootstrapping rule choices for younger and older mice
| Rule | % of models using rule |
|
|---|---|---|
| Younger mice | Older mice | |
| ActiveM ← (KC & Vlow) | TNF | 0.0 | 99.9 |
| ActiveM ← Vhigh | IL1a | 100.0 | 0.1 |
| TNF ← ActiveM | Vhigh | 53.2 | 1.3 |
| TNF ← ActivecDC | Vhigh | 46.8 | 1.3 |
| TNF ← ActiveM | 0.0 | 97.4 |
| IL1a ← ActiveM | Vlow | 50.3 | 0.1 |
| IL1a ← ActiveM | 0.0 | 99.9 |
| IL1a ← ActivecDC | Vlow | 49.7 | 0.1 |
| IL1b ← ActiveM | Vlow | 50.1 | 21.6 |
| IL1b ← ActiveM | 0.3 | 35.0 |
| IL1b ← ActivecDC | Vlow | 49.6 | 21.7 |
| IL1b ← pDC | Vlow | 0.0 | 21.7 |
| IL-6 ← ActiveM | Vlow | 45.2 | 0.0 |
| IL-6 ← ActiveM | 0.0 | 20.3 |
| IL-6 ← ActiveTh | 0.0 | 79.7 |
| IL-6 ← ActivecDC | Vlow | 44.8 | 0.0 |
| IL-6 ← pDC | Vlow | 10.0 | 0.0 |
| IL-10 ← ActiveTh & Vhigh | 75.9 | 0.7 |
| IL-10 ← ActiveNK & Vhigh | 24.1 | 49.7 |
| IL-10 ← ActiveB & Vhigh | 0.0 | 49.6 |
| IL12p70 ← ActiveTh & Vhigh | 36.1 | 0.5 |
| IL12p70 ← ActiveTh | 2.1 | 64.3 |
| IL12p70 ← ActiveM & IL1b | 0.0 | 35.2 |
| IL12p70 ← pDC | 61.8 | 0.0 |
| RANTES ← ActiveM | 66.7 | 49.3 |
| RANTES ← ActivecDC | 27.2 | 0.0 |
| RANTES ← ActiveCTL | 6.1 | 50.7 |
| MIP1b ← ActiveM | Vlow | 48.4 | 4.5 |
| MIP1b← ActiveM | 3.5 | 91.1 |
| MIP1b ← ActivecDC | Vlow | 48.1 | 4.5 |
| KC ← ActiveM | Vlow | 3.1 | 50.0 |
| KC ← Vlow | pDC | 96.9 | 50.0 |
| ActiveNK ← ActiveM | 0.0 | 99.3 |
| ActiveNK ← ActiveM & Vlow | 60.5 | 0.7 |
| ActiveNK ← ActivecDC & Vlow | 39.5 | 0.0 |
| IFNg ← ActiveM | 100.0 | 100.0 |
| ActiveN ← Vlow | TNF | 0.0 | 50.0 |
| ActiveN ← KC & Vlow | 100.0 | 50.0 |
| IFNab ← (ActiveTh & Vhigh) | IEC | 100.0 | 100.0 |
| ActiveCTL ← ActiveM | 100.0 | 1.6 |
| ActiveCTL ← ActiveTh | 0.0 | 98.4 |
| pDC ← ActivecDC | 0.0 | 100.0 |
| pDC ← ActiveN | 100.0 | 0.0 |
| ActivecDC ← ActiveNK | 7.3 | 82.5 |
| ActivecDC ← IL1b | 92.7 | 17.5 |
| ActiveTh ← Vlow | ActiveM | 0.0 | 100.0 |
| ActiveTh ← RANTES & ActiveM | 19.7 | 0.0 |
| ActiveTh ← ActivecDC | IL12p70 | 80.3 | 0.0 |
| ActiveB ← ActiveM | 100.0 | 100.0 |
| Ab ← (ActiveB & pDC) | Ab | 0.0 | 28.2 |
| Ab ← (ActiveB & IL-10)| Ab | 100.0 | 71.8 |
| Vlow ← (IEC | Vlow | Vhigh) & ∼(Ab & ∼IL-10) | 0.0 | 36.3 |
| Vlow ← (IEC | Vlow | Vhigh) & ∼(Ab) | 100.0 | 63.7 |
| Vhigh ← (IEC | Vhigh) & ∼(Ab) | 100.0 | 100.0 |
| IEC ← (Vlow | Vhigh) & ∼ActiveCTL & ∼ActiveNK | 100.0 | 100.0 |