Survival of chickens after intravenous (A) or oculonasal (B) inoculation with reassortant clones C5, C8, C11, C20, and C46 or HPAIV H5N1 parent strain A/chicken/Egypt/AR236/2015. Statistically significant differences compared to the survival of chickens inoculated with the parental virus (AR236) were observed for C5, C20, and C46 for both routes of inoculation (P < 0.01).