Table 1.
Additional Hormonal Measurements at Presentation
| Basal Hormones | ||
|---|---|---|
| Parameter | Result | Reference |
| Insulin | 15.4 μU/mL | 6–27 |
| TSH | 0.16 µU/mL | 0.4–4 |
| Free T4 | 0.9 ng/dL | 0.8–1.5 |
| T4 | 5.1 µg/dL | 4.5–12.5 |
| T3 | 88 ng/dL | 90–215 |
| FSH | <0.1 U/L | 1–11 |
| LH | 0.2 U/L | 1–8 |
| Free testosterone | 1.5 ng/dL | 7.4–22.6 |
| Androstendione | 186 ng/dL | 65–210 for Tanner V |
| Dehydroepiandrosterone | 2 ng/mL | <6.6 |
| Deydroepiandrosterone sulfate | 1.75 ng/dL | 0.8–5.6 |
| IGF1 | 120 ng/dL | 171–814 for Tanner V |
| Midnight salivary cortisol | 0.54 µg/dL | 0.01–0.09 |
| Dynamic Tests | ||
| 8 mg Dexamethasone Suppression Test | ||
| Time Point | Parameter | Result |
| Basal | Cortisol | 29.3 µg/dL |
| Final | 31.9 µg/dL | |
| CRH Stimulation Test | ||
| Time Point | Parameter | Result |
| −5 min | ACTH | 45.7 pg/mL |
| Cortisol | 28.8 µg/dL | |
| 0 | ACTH | 51.7 pg/mL |
| Cortisol | 28.2 µg/dL | |
| 15 min | ACTH | 58.5 pg/mL |
| Cortisol | 33.8 µg/dL | |
| 30 min | ACTH | 66.5 pg/mL |
| Cortisol | 30.6 µg/dL | |
| 40 min | ACTH | 66.6 pg/mL |
| Cortisol | 27.9 µg/dL | |
| Bilateral Inferior Petrosal Sinus Sampling | ||
| Time Point | Parameter | Result |
| −5 min | ACTH, RPV | 40.7 pg/mL |
| ACTH, LPV | 4446 pg/mL | |
| ACTH, peripheral | 38.8 pg/mL | |
| 0 | ACTH, RPV | 34.9 pg/mL |
| ACTH, LPV | 3545 pg/mL | |
| ACTH, peripheral | 35.7 pg/mL | |
| 3 min | ACTH, RPV | 476 pg/mL |
| ACTH, LPV | 2958 pg/mL | |
| ACTH, peripheral | 35.5 pg/mL | |
| 5 min | ACTH, RPV | 300 pg/mL |
| ACTH, LPV | 2737 pg/mL | |
| ACTH, peripheral | 33.3 pg/mL | |
| 10 min | ACTH, RPV | 359 pg/mL |
| ACTH, LPV | 2905 pg/mL | |
| ACTH, peripheral | 31.8 pg/mL | |
Abbreviations: FSH, follicle-stimulating hormone; IGF1, insulin-like growth factor1; LH, luteinizing hormone; LVP, left petrosal vein; RPV, right petrosal vein; TSH, thyrotropin.