(A) Alignment of 4 CRDs of CvGal2 with those of CvGal1. The color codes for the amino acid conservation are illustrated below. (B) Phylogenetic analysis of the individual CRDs of CvGal2 with those of galectins from various mollusk species. Four-CRDs galectins include: C. virginica CvGal1 (ABG75998.1), C. gigas gal-1 (EKC37204.1), C. gigas gal-2 (EKC31760.1), Pinctada fucata gal (ACO36044.1), Argopecten irradians (ACS72240); two CRDs include: C. gigas gal-9 (EKC40501.1), P.fucata gal-TR (ADU60337.1), Ruditapes philippinarum gal-TR (ACA09732.1), Tegillarca granosa gal (AGH06131.1), Biomphalaria glabrata gal-TR (ABQ09359.1).