Skip to main content
. Author manuscript; available in PMC: 2017 Nov 15.
Published in final edited form as: Biochemistry. 2015 Jul 24;54(30):4711–4730. doi: 10.1021/acs.biochem.5b00362

Figure 5. Models of individual CvGal2 CRDs.

Figure 5

A) Alignment with toad galectin1 (BaGal1) as template [PDBid 1GAN; (42)]. B) Overlay of the four CRDs (CRD1: CRD2: CRD3: CRD4) based on the model. C) Residues of the glycoside recognition site and other in β3 and β11 with possible glycan interactions. D) Accessible surface of the CvGal2:A colored by electrostatic potential A2 type-3 antigen [Fuc α1-2Galβ1-3GalNAcα1-3(Fucα1-2)Galβ1-4GlcNAc] in this galectins extended site. E) Electrostatic surface of the four CvGal2’s CRD models with a A2 antigen (CRD:A) and A2 type-3 antigen (CRDs:B-D) bound.