Fig. 3.

Impact of viral status on blood mononuclear cell phenotype during asthma exacerbation and at steady state. a-b) CD86 expression was measured on circulating cDCs, pDCs and monocytes from asthmatic children during the exacerbation (a) and steady state (b), using flow cytometry. During the exacerbation, patients were classified as being infected (V+) or not infected (V-). c) The levels of IL-6, IL-5 and IL-22 were measured in supernatants of PBMCs incubated in medium alone (baseline) and then stimulated with the TLR7-8 ligand gardiquimod. The median of our results was reported by the horizontal line, the 25 and 75 interquartile range by the box and the minimum and the maximum by the whiskers. *: p < 0.05 versus V- patients