Table 1.

Cell growth of STB5 and YAP1 deletion mutants and transformants in the microtiter plate assay

Strains, mutants and transformantsa,b	Cell growth (OD620)
	Coniferyl aldehyde (1.2 mM)		Furfural (17.0 mM)		HMF (24.0 mM)		BPL		SPL
	30 h	156 h	30 h	156 h	30 h	156 h	30 h	156 h	30 h	156 h
BY4741	1.06 ± 0.02	1.24 ± 0.02	1.12 ± 0.02	1.14 ± 0.02	0.82 ± 0.02	1.04 ± 0.02	0.56 ± 0.02	1.07 ± 0.02	0.60 ± 0.01	1.10 ± 0.01
BY4741-PB	0.37 ± 0.15	1.41 ± 0.02	0.73 ± 0.05	1.10 ± 0.02	0.54 ± 0.04	0.96 ± 0.05	0.26 ± 0.09	1.18 ± 0.03	0.61 ± 0.06	1.33 ± 0.01
M-Y	0.08 ± 0.01	0.04 ± 0.01	0.79 ± 0.02	1.11 ± 0.01	0.59 ± 0.02	0.90 ± 0.01	0.11 ± 0.01	1.02 ± 0.02	0.12 ± 0.01	1.37 ± 0.03
M-S	0.06 ± 0.01	0.68 ± 0.12	0.06 ± 0.01	1.10 ± 0.05	0.09 ± 0.01	0.16 ± 0.02	0.06 ± 0.01	0.75 ± 0.05	0.08 ± 0.01	1.01 ± 0.03
SIY	0.08 ± 0.01	0.05 ± 0.01	0.66 ± 0.02	1.13 ± 0.02	0.50 ± 0.02	0.86 ± 0.02	0.10 ± 0.01	0.96 ± 0.08	0.12 ± 0.01	1.29 ± 0.02
YIS	0.08 ± 0.01	1.14 ± 0.03	0.08 ± 0.01	1.02 ± 0.01	0.18 ± 0.01	0.67 ± 0.02	0.10 ± 0.02	0.81 ± 0.01	0.20 ± 0.01	0.82 ± 0.04
T-S	0.80 ± 0.13	1.28 ± 0.05	0.96 ± 0.04	1.16 ± 0.01	0.70 ± 0.05	1.01 ± 0.02	0.71 ± 0.04	1.00 ± 0.04	0.76 ± 0.04	1.16 ± 0.02
T-Y	0.92 ± 0.07	1.13 ± 0.06	0.67 ± 0.06	1.05 ± 0.02	0.93 ± 0.04	1.12 ± 0.07	0.73 ± 0.05	0.89 ± 0.03	0.82 ± 0.02	1.22 ± 0.04

^aBY4741, BY4741 host strain; BY4741-PB, BY4741 control transformant with plasmid backbone (PB) without insert; M-Y, deletion mutant of YAP1; M-S, deletion mutant of STB5; SIY, STB5 overexpressed in deletion mutant of YAP1; YIS, YAP1 overexpressed in deletion mutant of STB5; T-S, BY4741 transformant of STB5; T-Y, BY4741 transformant of YAP1

^bThe values were corrected as described in “Methods” section