Table 5.

Preliminary supplemental infection prevention and control measures for CRE “at-risk” patients with or without known microbiological results

Intervention (Evidence source)	Comments on measure and implementation
Pre-emptive isolation of patients on admission (SR)	✓ Isolation in single rooms either upon admission or when patients are actively screened for carriage of CRE ✓ Decision for patient placement should be made after individualised risk assessment by, and consultation with the IPC team ✓ En suite or bathrooms designated for use by known carriers, or commodes are strongly suggested for all patients on contact precautions for CRE
Active screening on admission (SR)a	✓ Active screening of all “at-risk” patients on admission to healthcare setting
Contact precautions (SR)	✓ Contact precautions should be used for direct contact with patient or their environment ✓ En suite or bathrooms designated for use by known carriers, or commodes are strongly suggested for all patients on contact precautions for CRE

SR Systematic review, EO Expert opinion

^aActive screening encompasses rectal screening, as well as screening from any other site which is either actively infected, e.g. draining wounds, or considered to be colonised

(Please see Additional file 1: Supplementary Table S3 in the supplementary section, for a printable summary of these measures)