FIGURE 2:

Nuclear expansion does not generate nuclear dynein–driven separation forces. Snapshots (A, D) and quantification (B, C, E, F) from computer simulation of centrosome separation in which the male pronucleus has a constant small size (A–C) or a constant large size (D–F). Individual centrosome distance curves (n = 10) as a function of time (B, E), as well as their averages with SD (C, F, blue). Here and hereafter, centrosome separation in control simulations (see Figure 1B) is shown for comparison (green).