Figure 5:

Weakening the lateral anchor drag leads to faster node aggregation and ring fracture in the absence of turnover. Simulation parameters as in Table 1, except node turnover is switched off by deleting turnover terms in Eqs. 4 and M.4, and the anchor drag coefficient γ_anc is varied as specified. (A, B) Profiles of actin filaments in the cross-section vs. time, in rings with anchor drag coefficient γ_anc = 400 pN s μm⁻¹ (A) and 1200 pN s μm⁻¹ (B). Horizontal dashed lines indicate time to ring fracture, defined as in Figure 4D. (C) Time evolution of tension in rings of A (blue) and B (red). (D) Aggregation time vs. node anchor drag coefficient γ_anc. Red: least-squares best-fit straight line.