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. 2017 Nov 7;28(23):3298–3314. doi: 10.1091/mbc.E17-06-0397

FIGURE 7:

FIGURE 7:

Model for the assembly of Spc110 into the SPB. The process is depicted as having three phases. During the initial phase, Spc110 is synthesized and binding sites in Spc42 and Spc29 become accessible in both the old and new poles. The second phase is a period of dynamic exchange and growth. The third phase ends exchange and strengthens the pole to withstand the pulling forces in the spindle. Checkpoint activation renews a period of expansion that later contracts when the checkpoint is satisfied.