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. 2017 Nov 10;11:626. doi: 10.3389/fnins.2017.00626

Table 1.

Some hallmarks of aging in peripheral tissues that are also present in brain tissue.

Hallmarks of aging in peripheral tissues
1 Genomic instability
2 Epigenetic alterations
3 Decrease in growth factors
4 Mitochondrial dysfunction
5 Loss of proteostasis
6 Stem cell exhaustion
7 Cellular senescence